Question

I am a breastfeeding mother and i want to know if it is safe to use LDK378? Is LDK378 safe for nursing mother and child? Does LDK378 extracts into breast milk? Does LDK378 has any long term or short term side effects on infants? Can LDK378 influence milk supply or can LDK378 decrease milk supply in lactating mothers?

Answer by DrLact: About LDK378 usage in lactation

No information is available on the clinical use of LDK378 during breastfeeding. Because LDK378 is 97% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during LDK378 therapy and for 2 weeks after the final dose.

Alternate Drugs

Vincristine(Dangerous)
Letrozole(Dangerous)
Tamoxifen(Dangerous)
Erlotinib(Unsafe)
Exemestane(Dangerous)
Mitoxantrone(Dangerous)
Trastuzumab(Unsafe)
Cladribine(Dangerous)
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Hydroxyurea(Low Risk)
Vinblastine(Dangerous)
Cetuximab(Unsafe)
Etoposide(Dangerous)
Bleomycin(Dangerous)
Carboplatin(Dangerous)
Doxorubicin(Dangerous)
Vinorelbine(Dangerous)
Imatinib(Unsafe)
Paclitaxel(Dangerous)
Cyclophosphamide(Dangerous)
Dacarbazine(Dangerous)
Fluorouracil(Dangerous)
Cisplatin(Unsafe)
Dasatinib(Unsafe)
Alemtuzumab(Low Risk)
Dactinomycin(Dangerous)
Busulfan(Dangerous)
Docetaxel(Dangerous)
Rituximab(Low Risk)
Bevacizumab(Low Risk)
Thioguanine(Dangerous)
Gemcitabine(Dangerous)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Erlotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)
Orlistat(Low Risk)
Gemcitabine(Dangerous)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Erlotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Erlotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Erlotinib(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.