Is MLN2238 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use MLN2238? Is MLN2238 safe for nursing mother and child? Does MLN2238 extracts into breast milk? Does MLN2238 has any long term or short term side effects on infants? Can MLN2238 influence milk supply or can MLN2238 decrease milk supply in lactating mothers?
Answer by DrLact: About MLN2238 usage in lactation
No information is available on the clinical use of MLN2238 during breastfeeding. Because its half-life is about 9.5 days, it is likely to accumulate in the infant. It is also given in combination with leflunomide and dexamethasone, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during MLN2238 therapy and for 90 days after the last dose.
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