Is GW572016 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use GW572016? Is GW572016 safe for nursing mother and child? Does GW572016 extracts into breast milk? Does GW572016 has any long term or short term side effects on infants? Can GW572016 influence milk supply or can GW572016 decrease milk supply in lactating mothers?
Answer by DrLact: About GW572016 usage in lactation
No information is available on the clinical use of GW572016 during breastfeeding. Because GW572016 is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 24 hours and it might accumulate in the infant. It is also given in combination with capecitabine, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during GW572016 therapy.
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