I am a breastfeeding mother and i want to know if it is safe to use GSK 572016? Is GSK 572016 safe for nursing mother and child? Does GSK 572016 extracts into breast milk? Does GSK 572016 has any long term or short term side effects on infants? Can GSK 572016 influence milk supply or can GSK 572016 decrease milk supply in lactating mothers?
No information is available on the clinical use of GSK 572016 during breastfeeding. Because GSK 572016 is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 24 hours and it might accumulate in the infant. It is also given in combination with capecitabine, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during GSK 572016 therapy.