Question

I am a breastfeeding mother and i want to know if it is safe to use PD 0332991? Is PD 0332991 safe for nursing mother and child? Does PD 0332991 extracts into breast milk? Does PD 0332991 has any long term or short term side effects on infants? Can PD 0332991 influence milk supply or can PD 0332991 decrease milk supply in lactating mothers?

Answer by DrLact: About PD 0332991 usage in lactation

No information is available on the clinical use of PD 0332991 during breastfeeding. Because PD 0332991 is 85% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 29 hours and it might accumulate in the infant. It is also given in combination with letrozole or fulvestrant, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during PD 0332991 therapy and for 3 weeks after the last dose.

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Synonyms of PD 0332991

PD-0332991
6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8H-pyrido(2,3-d)pyrimidin-7-one
PD0332991
PD 332991
UNII-G9ZF61LE7G
Ibrance
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