Question

I am a breastfeeding mother and i want to know if it is safe to use AZD 9291? Is AZD 9291 safe for nursing mother and child? Does AZD 9291 extracts into breast milk? Does AZD 9291 has any long term or short term side effects on infants? Can AZD 9291 influence milk supply or can AZD 9291 decrease milk supply in lactating mothers?

Answer by DrLact: About AZD 9291 usage in lactation

No information is available on the clinical use of AZD 9291 during breastfeeding. Because AZD 9291 is 95% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 48 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during AZD 9291 therapy and for 2 weeks after the final dose.

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