Is Mekinist Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Mekinist? Is Mekinist safe for nursing mother and child? Does Mekinist extracts into breast milk? Does Mekinist has any long term or short term side effects on infants? Can Mekinist influence milk supply or can Mekinist decrease milk supply in lactating mothers?
Answer by DrLact: About Mekinist usage in lactation
No information is available on the clinical use of Mekinist during breastfeeding. Because Mekinist is 97% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 3.9 to 4.8 days and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during Mekinist therapy and for 4 months after the last dose.
Alternate Drugs
Cisplatin(Unsafe)
Bleomycin(Dangerous)
Carboplatin(Dangerous)
Busulfan(Dangerous)
Vinorelbine(Dangerous)
Azelaic Acid(Safe)
Paclitaxel(Dangerous)
Dacarbazine(Dangerous)
Fluorouracil(Dangerous)
Letrozole(Dangerous)
Alemtuzumab(Low Risk)
Exemestane(Dangerous)
Dasatinib(Unsafe)
Rituximab(Low Risk)
Bevacizumab(Low Risk)
Thioguanine(Dangerous)
Vincristine(Dangerous)
Pazopanib(Unsafe)
Erlotinib(Unsafe)
Tamoxifen(Dangerous)
Nilotinib(Unsafe)
Mitoxantrone(Dangerous)
Mercaptopurine(Safe)
Trastuzumab(Unsafe)
Docetaxel(Dangerous)
Hydroxyurea(Low Risk)
Etoposide(Dangerous)
Dactinomycin(Dangerous)
Doxorubicin(Dangerous)
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Cyclophosphamide(Dangerous)
Vinblastine(Dangerous)
Imatinib(Unsafe)
Cladribine(Dangerous)
Gemcitabine(Dangerous)
Cetuximab(Unsafe)
Dasatinib(Unsafe)
Orlistat(Low Risk)
Allopurinol(Safe)
Pazopanib(Unsafe)
Erlotinib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Gemcitabine(Dangerous)
Dasatinib(Unsafe)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)