I am a breastfeeding mother and i want to know if it is safe to use UNII-N0TXR0XR5X? Is UNII-N0TXR0XR5X safe for nursing mother and child? Does UNII-N0TXR0XR5X extracts into breast milk? Does UNII-N0TXR0XR5X has any long term or short term side effects on infants? Can UNII-N0TXR0XR5X influence milk supply or can UNII-N0TXR0XR5X decrease milk supply in lactating mothers?
- DrLact safety Score for UNII-N0TXR0XR5X is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-N0TXR0XR5X is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-N0TXR0XR5X does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-N0TXR0XR5X safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
A 14-amino acid synthetic peptide related to the endogenous guanylin peptide family.Administered in moderate-severe constipation from irritable bowel syndrome and in idiopathic chronic constipation. It acts locally in the intestine, without being absorbed (EMA 2016). It is metabolized in the intestine obtaining its main active metabolite, des-tyrosine. Both UNII-N0TXR0XR5X and des-tyrosine are digested by intestinal enzymes and transformed into natural amino acids. Since the last update we have not found any published data on its excretion in breast milk. Its pharmacokinetic data (zero or negligible intestinal absorption with undetectable plasma levels and high molecular weight) make it very unlikely that significant amounts will pass to breast milk (EMA 2016).
UNII-N0TXR0XR5X is minimally absorbed from the gastrointestinal tract and the drug and its active metabolite is not measurable in plasma following administration of recommended doses. UNII-N0TXR0XR5X would not be expected to cause any adverse effects in breastfed infants. If UNII-N0TXR0XR5X is required by the mother, it is not a reason to discontinue breastfeeding.
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Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.