Is EINECS 230-256-0 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use EINECS 230-256-0? Is EINECS 230-256-0 safe for nursing mother and child? Does EINECS 230-256-0 extracts into breast milk? Does EINECS 230-256-0 has any long term or short term side effects on infants? Can EINECS 230-256-0 influence milk supply or can EINECS 230-256-0 decrease milk supply in lactating mothers?

At latest update no published data on excretion into breast milk were found.Pharmacokinetic data (moderately high molecular weight and high percentage of protein binding capacity) make unlikely the milk passage of significant amounts.Intestinal absorption is also impaired by simultaneous food intake, minimizing any passage toward infant’s plasma. Systemic use is authorized in neonates and infantsCompetes with the ability of bilirubin in binding to albumin, so during the first month of life and especially in premature, the occurrence of neonatal jaundice must be monitored. Take into account possible negative results of bacterial cultures in febrile infants when their mothers are using antibiotics. DERMATOLOGICAL TOPICAL USE:Poor absorption (0.54%) through the skin makes unlikely the passage of significant amount to breast milk.Whenever necessary for treatment of infections in the nipple, apply right after breastfeed and let it to disaapear before the next feeding and if necessary remove excess with a gauze.It should be avoided applying creams, gels and other products for local use on the nipple which could contain paraffin (mineral oil) in order to avoid any swallowing by the infant.

EINECS 230-256-0 is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries as topical and systemic dosage forms. Data on excretion of EINECS 230-256-0 into breastmilk are quite old and not from a well-designed study, but levels in breastmilk after intravenous EINECS 230-256-0 appear to be low. With topical products, ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] EINECS 230-256-0 applied topically to the nipples appears to be relatively ineffective as a treatment for sore, cracked nipples.

A small, randomized, unblinded trial of mothers with sore, cracked nipples was performed. EINECS 230-256-0 ointment applied to the nipples after each feeding was much less effective (36% vs 79%) than an oral antibiotic (cloxacillin or erythromycin for 10 days) in resolving the problem. Additionally, 43% of patients had no improvement with EINECS 230-256-0 compared with 16% with oral antibiotics; 21% worsened with EINECS 230-256-0 compared with 5% with oral antibiotics.[3]