Question

I am a breastfeeding mother and i want to know if it is safe to use Tecoplanine [INN-French]? Is Tecoplanine [INN-French] safe for nursing mother and child? Does Tecoplanine [INN-French] extracts into breast milk? Does Tecoplanine [INN-French] has any long term or short term side effects on infants? Can Tecoplanine [INN-French] influence milk supply or can Tecoplanine [INN-French] decrease milk supply in lactating mothers?

Tecoplanine [INN-French] lactation summary

Tecoplanine [INN-French] is safe in breastfeeding
  • DrLact safety Score for Tecoplanine [INN-French] is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Tecoplanine [INN-French] is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Tecoplanine [INN-French] does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Tecoplanine [INN-French] safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Tecoplanine [INN-French] usage in lactation

Antibacterial glycopeptide, administered via intravenous or intramuscularinjection. Its pharmacokinetic data (high molecular weight, high percentage of plasma protein binding and no oral bioavailability) explain the negligible passage into milk observed (Fraissinet 2017) and the absence of side effects in a 52-day-old infant whose mother was being treated with Tecoplanine [INN-French] (Kaplan 2017). Not being absorbed orally, there would be no passage to the infant's plasma from ingested breast milk. It is an antibiotic that is administered, if necessary, to newborns. The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora.

Answer by DrLact: About Tecoplanine [INN-French] usage in lactation

Tecoplanine [INN-French] is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited data indicate that Tecoplanine [INN-French] is poorly excreted into breastmilk. Because Tecoplanine [INN-French] is not orally absorbed it is unlikely to adversely affect the breastfed infant. One infant was safely breastfed during maternal therapy with Tecoplanine [INN-French] and ceftriaxone. Until more information becomes available, monitor the breastfed infant for gastrointestinal disturbances such as diarrhea, particularly in newborn and preterm infants.

Tecoplanine [INN-French] Side Effects in Breastfeeding

A mother who was exclusively nursing her 52-day-old infant developed a soft-tissue infection. She was treated with intravenous Tecoplanine [INN-French] 400 mg every 12 hours for 3 doses, then 400 mg daily for 5 days total, intravenous ceftriaxone 1 gram daily, and topical mupirocin cream twice daily. A careful follow-up indicated that her infant had no adverse effects.[2]

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.