I am a breastfeeding mother and i want to know if it is safe to use UNII-3M6325NY1R? Is UNII-3M6325NY1R safe for nursing mother and child? Does UNII-3M6325NY1R extracts into breast milk? Does UNII-3M6325NY1R has any long term or short term side effects on infants? Can UNII-3M6325NY1R influence milk supply or can UNII-3M6325NY1R decrease milk supply in lactating mothers?
UNII-3M6325NY1R is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited data indicate that breastmilk iron is increased 3 days after an intravenous infusion of iron isomaltoside, but within the normal range. By 7 days after the dose, breastmilk iron levels were similar to that of mothers taking oral iron. UNII-3M6325NY1R appears to be acceptable to use in nursing mothers with no special precautions required. Pasteurization of milk by the Holder method reduces the concentration of iron in milk by about 6.5%.[1]
In a randomized, nonblinded study, randomly assigned to receive either a single intravenous dose of 1200 mg iron isomaltoside (n = 97) or oral iron 40 to 50 mg oral iron daily or 100 mg oral iron one or two times daily (n = 99). There was no significant difference between groups in the median time to lactogenesis, nor in the time of discontinuation of breastfeeding among those who weaned their infants.[3]
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