Is L-5458 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use L-5458? Is L-5458 safe for nursing mother and child? Does L-5458 extracts into breast milk? Does L-5458 has any long term or short term side effects on infants? Can L-5458 influence milk supply or can L-5458 decrease milk supply in lactating mothers?
L-5458 lactation summary
- DrLact safety Score for L-5458 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of L-5458 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that L-5458 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of L-5458 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using L-5458 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About L-5458 usage in lactation
Drug which is oxazolinic-derived from Prednisolone with similar properties to the latter. At latest update no published data on excretion into breast milk were found. Due to a moderate high molecular weight and rapid elimination time it is probably safe while breastfeeding, mostly in non long-term treatments. Until more data on this drug is available, it would be preferred other options that are known to be safer, specially during the neonatal period and prematurity.
Answer by DrLact: About L-5458 usage in lactation
Because no information is available on the use of L-5458 during breastfeeding, an alternate corticosteroid may be preferred, especially while nursing a newborn or preterm infant.
L-5458 Side Effects in Breastfeeding
None reported with any corticosteroid.
Alternate Drugs
Prednisone(Safe)
Dexamethasone(Low Risk)
Betamethasone(Low Risk)
Fluticasone, Inhaled(Safe)
Prednisolone(Safe)
Dexamethasone, Topical(Low Risk)
Fluticasone, Topical(Safe)
Betamethasone, Topical(Low Risk)
Natalizumab(Low Risk)
Ciclesonide(Safe)
Deflazacort(Low Risk)
Hydrocortisone, Topical(Safe)
Methylprednisolone(Safe)
Clobetasol(Safe)
Flunisolide(Safe)
Hydrocortisone(Safe)
Prednisone(Safe)
Dexamethasone(Low Risk)
Betamethasone(Low Risk)
Prednisolone(Safe)
Deflazacort(Low Risk)
Methylprednisolone(Safe)
Hydrocortisone(Safe)
Prednisone(Safe)
Dexamethasone(Low Risk)
Betamethasone(Low Risk)
Fluticasone, Inhaled(Safe)
Prednisolone(Safe)
Dexamethasone, Topical(Low Risk)
Fluticasone, Topical(Safe)
Betamethasone, Topical(Low Risk)
Ciclesonide(Safe)
Deflazacort(Low Risk)
Hydrocortisone, Topical(Safe)
Methylprednisolone(Safe)
Clobetasol(Safe)
Flunisolide(Safe)
Hydrocortisone(Safe)