Question

I am a breastfeeding mother and i want to know if it is safe to use Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer? Is Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer safe for nursing mother and child? Does Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer extracts into breast milk? Does Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer has any long term or short term side effects on infants? Can Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer influence milk supply or can Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer decrease milk supply in lactating mothers?

Answer by DrLact: About Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer usage in lactation

No information is available on the clinical use of Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer during breastfeeding. Because Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer is a large protein molecule with a molecular weight of about 147,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Immunoglobulin, anti-(humaninterleukin 4 receptor alpha) (human regn668 heavy chain), disulfide with human regn668 kappa-chain, dimer is a human immunoglobulin G4 (IgG4) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with Holder pasteurization having little effect on IgG4 activity.[3] None of the studies measured IgG activity.
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