Is Nefopamum [INN-Latin] Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Nefopamum [INN-Latin]? Is Nefopamum [INN-Latin] safe for nursing mother and child? Does Nefopamum [INN-Latin] extracts into breast milk? Does Nefopamum [INN-Latin] has any long term or short term side effects on infants? Can Nefopamum [INN-Latin] influence milk supply or can Nefopamum [INN-Latin] decrease milk supply in lactating mothers?

The amount of Nefopamum [INN-Latin] in breastmilk with usual maternal dosages is small. Nefopamum [INN-Latin] does not appear to adversely affect the milk supply or the neurobehavioral scores of breastfed neonates. Breastfeeding is acceptable during maternal use of Nefopamum [INN-Latin].

Sixty-six women who had cesarean section deliveries were two groups postpartum: intravenous (IV) Nefopamum [INN-Latin] 20 mg every 6 hours or IV acetaminophen 1 gram every 6 hours as well as IV ketoprofen 50 mg every 6 hours in both groups Neonatal neurobehavioral scores were recorded at 12, 24, 48, and 72 hours post-caesarean by a pediatrician blinded to the group allocation. No difference was found between the groups in the behavioral scores.[2]

Sixty-six women who had cesarean section deliveries were two groups: IV Nefopamum [INN-Latin] 20 mg every 6 hours or IV acetaminophen 1 gram every 6 hours. All women received the same preoperative analgesia consisting of spinal bupivacaine, sufentanil, and morphine as well as intravenous ephedrine and phenylephrine to prevent hypotension. Postoperatively, all received IV oxytocin by infusion and IV ketoprofen 50 mg every 6 hours. Milk production was assessed by weighing the newborn before and after each breastfeed on days 2 and 3. No statistical differences were seen between the two groups in the weight difference before and after each feed, the newborn daily weight curve evolution, or the fall in weight between days 0 and 2. Mothers also rated their breast fullness to assess the onset of lactogenesis II; no difference was found between the two groups in the time to lactogenesis II. There was also no difference in serum prolactin between the groups.[2]