Is PKC412 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use PKC412? Is PKC412 safe for nursing mother and child? Does PKC412 extracts into breast milk? Does PKC412 has any long term or short term side effects on infants? Can PKC412 influence milk supply or can PKC412 decrease milk supply in lactating mothers?
Answer by DrLact: About PKC412 usage in lactation
No information is available on the clinical use of PKC412 during breastfeeding. Because PKC412 and its active metabolites are 99.8% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during PKC412 therapy and for at least 4 months after the last dose. Avoiding breastfeeding is particularly important when PKC412 is given with other cancer chemotherapy agents.
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