Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-NU90V55F8I? Is UNII-NU90V55F8I safe for nursing mother and child? Does UNII-NU90V55F8I extracts into breast milk? Does UNII-NU90V55F8I has any long term or short term side effects on infants? Can UNII-NU90V55F8I influence milk supply or can UNII-NU90V55F8I decrease milk supply in lactating mothers?

Answer by DrLact: About UNII-NU90V55F8I usage in lactation

No information is available on the clinical use of UNII-NU90V55F8I during breastfeeding. Because UNII-NU90V55F8I is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If UNII-NU90V55F8I is required by the mother, it is not a reason to discontinue breastfeeding.[1] Until more data become available, UNII-NU90V55F8I should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. UNII-NU90V55F8I is a human immunoglobulin G1 (IgG1) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G in mature milk by 60 to 79%.[2][3] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[4] None of the studies measured IgG activity.

Synonyms of UNII-NU90V55F8I

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