Is AP-26113 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use AP-26113? Is AP-26113 safe for nursing mother and child? Does AP-26113 extracts into breast milk? Does AP-26113 has any long term or short term side effects on infants? Can AP-26113 influence milk supply or can AP-26113 decrease milk supply in lactating mothers?

Answer by DrLact: About AP-26113 usage in lactation

No information is available on the clinical use of AP-26113 during breastfeeding. The manufacturer recommends that breastfeeding be discontinued during AP-26113 therapy and for 1 week after the final dose.

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Synonyms of AP-26113

UNII-HYW8DB273J

2,4-Pyrimidinediamine, 5-chloro-N4-(2-(dimethylphosphinyl)phenyl)-N2-(2-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)-

(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethyl-,delta5-phosphanone

5-Chloro-N4-(2-(dimethylphosphoryl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1- yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine

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