Question

I am a breastfeeding mother and i want to know if it is safe to use HKI-272? Is HKI-272 safe for nursing mother and child? Does HKI-272 extracts into breast milk? Does HKI-272 has any long term or short term side effects on infants? Can HKI-272 influence milk supply or can HKI-272 decrease milk supply in lactating mothers?

Answer by DrLact: About HKI-272 usage in lactation

No information is available on the clinical use of HKI-272 during breastfeeding. Because HKI-272 and its metabolite are over 99% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during HKI-272 therapy.

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