Is UNII-361LPM2T56 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-361LPM2T56? Is UNII-361LPM2T56 safe for nursing mother and child? Does UNII-361LPM2T56 extracts into breast milk? Does UNII-361LPM2T56 has any long term or short term side effects on infants? Can UNII-361LPM2T56 influence milk supply or can UNII-361LPM2T56 decrease milk supply in lactating mothers?
UNII-361LPM2T56 lactation summary
- DrLact safety Score for UNII-361LPM2T56 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-361LPM2T56 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-361LPM2T56 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-361LPM2T56 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-361LPM2T56 usage in lactation
A modified gamma-cyclodextrin that binds to rocuronium or vecuronium, reversing its neuromuscular blocking action. Used intravenously. Since the last update we have not found published data on its excretion in breast milk. Side effects are rare and mild.It is administered in single or isolated doses. Its high molecular weight makes it unlikely that it will pass into milk in significant amounts. Its low oral bioavailability would make it difficult its passage to the infant’s plasma through breast milk (EMA 2017).UNII-361LPM2T56 can be used during breastfeeding (EMA 2017)
Answer by DrLact: About UNII-361LPM2T56 usage in lactation
No information is available on the clinical use of UNII-361LPM2T56 during breastfeeding. Because UNII-361LPM2T56 is a large, highly polar molecule with a molecular weight of 2002, the amount in milk is likely to be very low and oral absorption by the infant is unlikely. UNII-361LPM2T56 is acceptable to use during breastfeeding.[1]