Is AI3-52216 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use AI3-52216? Is AI3-52216 safe for nursing mother and child? Does AI3-52216 extracts into breast milk? Does AI3-52216 has any long term or short term side effects on infants? Can AI3-52216 influence milk supply or can AI3-52216 decrease milk supply in lactating mothers?
AI3-52216 lactation summary
- DrLact safety Score for AI3-52216 is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of AI3-52216 may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that AI3-52216 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using AI3-52216 .
- Usage of AI3-52216 is in contradiction to breastfeeding hence if it is must to use AI3-52216 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About AI3-52216 usage in lactation
Drug is cleared from the body after 25-50 elimination half-life. Resuming breastfeeding is likely safe after 48 hours of pump-and-dump.
Answer by DrLact: About AI3-52216 usage in lactation
No information is available on the use of AI3-52216 during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as AI3-52216.[1] The manufacturer recommends that breastfeeding be discontinued during AI3-52216 therapy and for 1 month after the last dose.
AI3-52216 Possible Effects in Breastfeeding
Some evidence indicates that AI3-52216 can increase serum prolactin.[2]