Is Bischloroethyl nitrosourea Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Bischloroethyl nitrosourea? Is Bischloroethyl nitrosourea safe for nursing mother and child? Does Bischloroethyl nitrosourea extracts into breast milk? Does Bischloroethyl nitrosourea has any long term or short term side effects on infants? Can Bischloroethyl nitrosourea influence milk supply or can Bischloroethyl nitrosourea decrease milk supply in lactating mothers?
Bischloroethyl nitrosourea lactation summary
- DrLact safety Score for Bischloroethyl nitrosourea is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Bischloroethyl nitrosourea may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Bischloroethyl nitrosourea may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Bischloroethyl nitrosourea .
- Usage of Bischloroethyl nitrosourea is in contradiction to breastfeeding hence if it is must to use Bischloroethyl nitrosourea and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Bischloroethyl nitrosourea usage in lactation
Drug is cleared from the body after 25-50 elimination half-life. Resuming breastfeeding is likely safe after 48 hours of pump-and-dump.
Answer by DrLact: About Bischloroethyl nitrosourea usage in lactation
No information is available on the use of Bischloroethyl nitrosourea during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as Bischloroethyl nitrosourea.[1] The manufacturer recommends that breastfeeding be discontinued during Bischloroethyl nitrosourea therapy and for 1 month after the last dose.
Bischloroethyl nitrosourea Possible Effects in Breastfeeding
Some evidence indicates that Bischloroethyl nitrosourea can increase serum prolactin.[2]