Is NCI-C04773 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NCI-C04773? Is NCI-C04773 safe for nursing mother and child? Does NCI-C04773 extracts into breast milk? Does NCI-C04773 has any long term or short term side effects on infants? Can NCI-C04773 influence milk supply or can NCI-C04773 decrease milk supply in lactating mothers?
NCI-C04773 lactation summary
- DrLact safety Score for NCI-C04773 is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of NCI-C04773 may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that NCI-C04773 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using NCI-C04773 .
- Usage of NCI-C04773 is in contradiction to breastfeeding hence if it is must to use NCI-C04773 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NCI-C04773 usage in lactation
Drug is cleared from the body after 25-50 elimination half-life. Resuming breastfeeding is likely safe after 48 hours of pump-and-dump.
Answer by DrLact: About NCI-C04773 usage in lactation
No information is available on the use of NCI-C04773 during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as NCI-C04773.[1] The manufacturer recommends that breastfeeding be discontinued during NCI-C04773 therapy and for 1 month after the last dose.
NCI-C04773 Possible Effects in Breastfeeding
Some evidence indicates that NCI-C04773 can increase serum prolactin.[2]