Is NSC 409962 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC 409962? Is NSC 409962 safe for nursing mother and child? Does NSC 409962 extracts into breast milk? Does NSC 409962 has any long term or short term side effects on infants? Can NSC 409962 influence milk supply or can NSC 409962 decrease milk supply in lactating mothers?
NSC 409962 lactation summary
- DrLact safety Score for NSC 409962 is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of NSC 409962 may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that NSC 409962 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using NSC 409962 .
- Usage of NSC 409962 is in contradiction to breastfeeding hence if it is must to use NSC 409962 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC 409962 usage in lactation
Drug is cleared from the body after 25-50 elimination half-life. Resuming breastfeeding is likely safe after 48 hours of pump-and-dump.
Answer by DrLact: About NSC 409962 usage in lactation
No information is available on the use of NSC 409962 during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as NSC 409962.[1] The manufacturer recommends that breastfeeding be discontinued during NSC 409962 therapy and for 1 month after the last dose.
NSC 409962 Possible Effects in Breastfeeding
Some evidence indicates that NSC 409962 can increase serum prolactin.[2]