Is PM 185184 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use PM 185184? Is PM 185184 safe for nursing mother and child? Does PM 185184 extracts into breast milk? Does PM 185184 has any long term or short term side effects on infants? Can PM 185184 influence milk supply or can PM 185184 decrease milk supply in lactating mothers?

On last update relevant published data concerning breastfeeding were not found. Pharmacokinetic data suggest that excretion into breast milk would be significant. However, it is considered safe for treatment of parasite infections like Amebiasis in children, with a dosage for children weighing over 5 kg that has been established by the manufacturer. It is a medication included in a same group and similar properties of Metronidazole.

No information is available on the clinical use of PM 185184 during breastfeeding and no studies have evaluated adverse effects of PM 185184 on the infant during breastfeeding, but presumably they are similar to those of the closely related drug, metronidazole, such as increased risk of oral and rectal infections. As with metronidazole, concern has been raised about exposure of healthy infants to PM 185184 via breastmilk, because of possible mutagenicity and carcinogenicity. Based on the PM 185184's elimination half-life of approximately 17 hours, the manufacturer recommends avoidance of breastfeeding for 96 after a single dose. Other drugs are available for bacterial vaginosis, and can be given vaginally, which should result in lower amounts in breastmilk.