Is RS-21592 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use RS-21592? Is RS-21592 safe for nursing mother and child? Does RS-21592 extracts into breast milk? Does RS-21592 has any long term or short term side effects on infants? Can RS-21592 influence milk supply or can RS-21592 decrease milk supply in lactating mothers?

Synthetic nucleoside which is analogue of guanine, structurally very closed related to acyclovir.Indicated for the treatment and prevention of Cytomegalovirus (CMV) in immunocompromised patients. At latest update no published data on excretion into breast milk were found. It is used in newborns and premature who are affected with CMV infection.Its low oral bioavailability hinders the passage from ingested milk towards the infant’s plasma, except in preterm babies and immediate neonatal period, which may show an increased intestinal permeability.

Several factors might affect the decision to use RS-21592 in a nursing mother. No information is available on the clinical use of RS-21592 during breastfeeding. Cytomegalovirus (CMV) can be transmitted to infants though breastmilk, with preterm and immunocompromised infants at greatest risk. No information is available on any changes in the risk of transmission if the mother is being treated with RS-21592. Although the manufacturer recommends avoiding breastfeeding during RS-21592 use because of the risk of infant drug toxicity, neonates with CMV infections are often treated directly with RS-21592. If the mother has a concurrent infection with HIV, breastfeeding is not recommended in the United States and other developed countries.