Question

I am a breastfeeding mother and i want to know if it is safe to use 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid? Is 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid safe for nursing mother and child? Does 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid extracts into breast milk? Does 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid has any long term or short term side effects on infants? Can 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid influence milk supply or can 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid decrease milk supply in lactating mothers?

Answer by DrLact: About 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid usage in lactation

No information is available on the use of 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid during breastfeeding. Because 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid is 99% bound to plasma proteins, the amount in milk is likely to be very low. If 2-((4S)-8-Fluoro-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3-(2-methoxy-5-(trifluoromethyl)phenyl)-4H-quinazolin-4-yl)acetic acid is required by the mother, it is not a reason to discontinue breastfeeding. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Alternate Drugs

Lindane(Unsafe)
Cefixime(Safe)
Nevirapine(Low Risk)
Demeclocycline(Low Risk)
Zidovudine(Low Risk)
Moxifloxacin(Low Risk)
Valganciclovir(Low Risk)
Cefepime(Safe)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Methicillin(Low Risk)
Cefdinir(Safe)
Econazole(Safe)
Erythromycin(Low Risk)
Efavirenz(Unsafe)
Meropenem(Safe)
Ganciclovir(Low Risk)
Cefazolin(Safe)
Tenofovir(Safe)
Clindamycin(Low Risk)
Didanosine(Unsafe)
Lomefloxacin(Low Risk)
Cefaclor(Safe)
Levofloxacin(Low Risk)
Kanamycin(Safe)
Primaquine(Low Risk)
Acyclovir(Safe)
Atovaquone(Low Risk)
Saquinavir(Unsafe)
Quinine(Safe)
Linezolid(Low Risk)
Amantadine(Low Risk)
Rifaximin(Safe)
Cefprozil(Safe)
Aztreonam(Safe)
Indinavir(Unsafe)
Naftifine(Safe)
Ofloxacin(Safe)
Cefoxitin(Safe)
Ritonavir(Unsafe)
Gatifloxacin(Low Risk)
Dapsone(Low Risk)
Cefotetan(Safe)
Abacavir(Safe)
Enoxacin(Low Risk)
Capreomycin(Low Risk)
Malathion(Low Risk)
Doxycycline(Low Risk)
Ertapenem(Safe)
Neomycin(Safe)
Amikacin(Safe)
Nafcillin(Safe)
Valganciclovir(Low Risk)
Daclatasvir(Low Risk)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Dasabuvir(Low Risk)
Ganciclovir(Low Risk)
Ribavirin(Low Risk)
Efavirenz(Unsafe)
Tenofovir(Safe)
Didanosine(Unsafe)
Acyclovir(Safe)
Saquinavir(Unsafe)
Amantadine(Low Risk)
Velpatasvir(Low Risk)
Indinavir(Unsafe)
Zanamivir(Safe)
Simeprevir(Low Risk)
Ritonavir(Unsafe)
Sofosbuvir(Low Risk)
Abacavir(Safe)
Ledipasvir(Low Risk)
Ombitasvir(Low Risk)
Nevirapine(Low Risk)
Zidovudine(Low Risk)
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