Is N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide? Is N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide safe for nursing mother and child? Does N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide extracts into breast milk? Does N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide has any long term or short term side effects on infants? Can N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide influence milk supply or can N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide decrease milk supply in lactating mothers?
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide lactation summary
- DrLact safety Score for N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide usage in lactation
Potassium-sparing diuretic. On latest update relevant data on breastfeeding were not found. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting and loop-acting effect) may inhibit lactation. Use the lower dose as possible especially during the first postnatal month.
Answer by DrLact: About N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide usage in lactation
No information is available on the use of N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide during breastfeeding, so an alternate drug may be preferred.
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide Possible Effects in Breastfeeding
Intense diuresis can suppress lactation;[1][2] however, it is unlikely that N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide alone is sufficiently potent to cause this effect.