Question

I am a breastfeeding mother and i want to know if it is safe to use Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody? Is Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody safe for nursing mother and child? Does Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody extracts into breast milk? Does Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody has any long term or short term side effects on infants? Can Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody influence milk supply or can Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody decrease milk supply in lactating mothers?

Answer by DrLact: About Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody usage in lactation

No information is available on the clinical use of Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody during breastfeeding. Because Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Immunoglobulin G1-kappa, anti-(homo sapiens il5ra (interleukin 5receptor subunit alpha, cd125)), humanized monoclonalantibody is a human immunoglobulin G1 (IgG1) kappa antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[3] None of the studies measured IgG activity.
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