I am a breastfeeding mother and i want to know if it is safe to use UNII-I5I8VB78VT? Is UNII-I5I8VB78VT safe for nursing mother and child? Does UNII-I5I8VB78VT extracts into breast milk? Does UNII-I5I8VB78VT has any long term or short term side effects on infants? Can UNII-I5I8VB78VT influence milk supply or can UNII-I5I8VB78VT decrease milk supply in lactating mothers?
No information is available on the passage of UNII-I5I8VB78VT into breastmilk. Because UNII-I5I8VB78VT is a large protein molecule with a molecular weight of 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, UNII-I5I8VB78VT injection should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. UNII-I5I8VB78VT is a human immunoglobulin G2 (IgG2) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG2 activity decreasing by about 50%.[3] None of the studies measured IgG activity.
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