Question

I am a breastfeeding mother and i want to know if it is safe to use rAvPAL-PEG? Is rAvPAL-PEG safe for nursing mother and child? Does rAvPAL-PEG extracts into breast milk? Does rAvPAL-PEG has any long term or short term side effects on infants? Can rAvPAL-PEG influence milk supply or can rAvPAL-PEG decrease milk supply in lactating mothers?

Answer by DrLact: About rAvPAL-PEG usage in lactation

No information is available on the use of rAvPAL-PEG-pqpz during breastfeeding. Absorption of the drug by the infant from breastmilk is unlikely because it is a polypeptide that is probably destroyed in the infant's gastrointestinal tract. rAvPAL-PEG-pqpz may decrease the phenylalanine content of breastmilk. The manufacturer recommends monitoring blood phenylalanine concentrations in breastfeeding women treated with rAvPAL-PEG-pqpz.

Alternate Drugs

Velaglucerase alfa
Agalsidase Alfa
Imiglucerase
Alglucerase
Pegvaliase
Vestronidase Alfa-vjbk
Alteplase(Safe)
Idursulfase
Laronidase(Low Risk)
Rasburicase
Pegademase Bovine
Dornase Alfa(Safe)
Agalsidase Beta
Taliglucerase alfa
Alglucosidase Alfa
Pegvaliase
Pegvaliase
Pegvaliase

Synonyms of rAvPAL-PEG

UNII-N6UAH27EUV
Pegvaliase [INN]
PEG-PAL
BMN 165
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