Is PRT-4445 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use PRT-4445? Is PRT-4445 safe for nursing mother and child? Does PRT-4445 extracts into breast milk? Does PRT-4445 has any long term or short term side effects on infants? Can PRT-4445 influence milk supply or can PRT-4445 decrease milk supply in lactating mothers?
Answer by DrLact: About PRT-4445 usage in lactation
No information is available on the clinical use of coagulation factor Xa during breastfeeding. Because it is a large protein molecule with a molecular weight of about 40,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, coagulation factor X should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.