Is CEP 1538 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CEP 1538? Is CEP 1538 safe for nursing mother and child? Does CEP 1538 extracts into breast milk? Does CEP 1538 has any long term or short term side effects on infants? Can CEP 1538 influence milk supply or can CEP 1538 decrease milk supply in lactating mothers?

• DrLact safety Score for CEP 1538 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of CEP 1538 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that CEP 1538 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using CEP 1538 .
• It is recommended to evaluate the advantage of not breastfeeding while using CEP 1538 Vs not using CEP 1538 And continue breastfeeding.
• While using CEP 1538 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Used for treatment of narcolepsy. On latest update relevant data on breastfeeding was not found. Pharmacokinetic data indicates that drug excretion into breast milk would be significant. Until more information concerning breastfeeding is available, a safer alternative is preferred.

No information is available on the excretion of CEP 1538 into breastmilk. Minimal information from women who breastfed their infant's while using CEP 1538 found no adverse effects in the infants. Until more safety data are available, CEP 1538 should be used with careful infant monitoring during breastfeeding, or an alternate drug may be preferred.

In one case-control study of women having narcolepsy with cataplexy, some women (fewer than 6) breastfed their infants while taking CEP 1538. No adverse effects were noted. The authors felt that the risk from the medication is low.[1]

A case control study comparing women with narcolepsy with cataplexy to a control group found that those with narcolepsy breastfed longer than those without the disease. The authors felt that the difference likely due to a lower employment rate among the women with narcolepsy.[1]