Is CEP 10953 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CEP 10953? Is CEP 10953 safe for nursing mother and child? Does CEP 10953 extracts into breast milk? Does CEP 10953 has any long term or short term side effects on infants? Can CEP 10953 influence milk supply or can CEP 10953 decrease milk supply in lactating mothers?

• DrLact safety Score for CEP 10953 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of CEP 10953 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that CEP 10953 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using CEP 10953 .
• It is recommended to evaluate the advantage of not breastfeeding while using CEP 10953 Vs not using CEP 10953 And continue breastfeeding.
• While using CEP 10953 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Used for treatment of narcolepsy. On latest update relevant data on breastfeeding was not found. Pharmacokinetic data indicates that drug excretion into breast milk would be significant. Until more information concerning breastfeeding is available, a safer alternative is preferred.

CEP 10953 is the R-enantiomer of modafinil. No information is available on the use of CEP 10953 during breastfeeding. Minimal information from women who breastfed their infant's while using modafinil found no adverse effects in the infants. Until more safety data are available, CEP 10953 should be used with careful infant monitoring during breastfeeding, or an alternate drug may be preferred.

In one case-control study of women having narcolepsy with cataplexy, some women (fewer than 6) breastfed their infants while taking modafinil. No adverse effects were noted. The authors felt that the risk from the medication is low.[1]

A case control study comparing women with narcolepsy with cataplexy to a control group found that those with narcolepsy breastfed longer than those without the disease. The authors felt that the difference likely due to a lower employment rate among the women with narcolepsy.[1]