Question

I am a breastfeeding mother and i want to know if it is safe to use 516 MD? Is 516 MD safe for nursing mother and child? Does 516 MD extracts into breast milk? Does 516 MD has any long term or short term side effects on infants? Can 516 MD influence milk supply or can 516 MD decrease milk supply in lactating mothers?

516 MD lactation summary

516 MD usage has low risk in breastfeeding
  • DrLact safety Score for 516 MD is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of 516 MD may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that 516 MD may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of 516 MD low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using 516 MD We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 516 MD usage in lactation

A calcium channel blocker drug and an antihistamine piperazine derivative which has a sedative effect. Chemical structure and effects similar to Flunarizine (see specific info).Used to treat nausea and vertigo of Meniere's Disease, and symptoms of TravelerĀ“s Sickness.It has been withdrawn from the market in several countries because of Parkinson-like symptoms. At latest update relevant published data were not found on excretion into breast milk. Its high binding capacity to plasma proteins makes it unlikely excretion into breastmilk. It should be wise on the long-term, the use of a known safer alternative until more data is available on this drug, mostly for children in the neonatal period or in case of prematurity that may be affected by an increased gut permeability. Occasional use to prevent motion sickness may be compatible with breastfeeding.

Answer by DrLact: About 516 MD usage in lactation

516 MD is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. No information is available on the use of 516 MD during breastfeeding. Expert opinion recommends that 516 MD not be used in migraine prophylaxis.[1][2][3] An alternate drug is preferred, especially while nursing a newborn or preterm infant.

Alternate Drugs

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.