Is Ivosidenib [WHO-DD] Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Ivosidenib [WHO-DD]? Is Ivosidenib [WHO-DD] safe for nursing mother and child? Does Ivosidenib [WHO-DD] extracts into breast milk? Does Ivosidenib [WHO-DD] has any long term or short term side effects on infants? Can Ivosidenib [WHO-DD] influence milk supply or can Ivosidenib [WHO-DD] decrease milk supply in lactating mothers?
Answer by DrLact: About Ivosidenib [WHO-DD] usage in lactation
No information is available on the clinical use of Ivosidenib [WHO-DD] during breastfeeding. Because Ivosidenib [WHO-DD] is 92 to 96% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 93 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during erlotinib therapy and for 1 month after the dose.
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