Is Actinomycin I Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Actinomycin I? Is Actinomycin I safe for nursing mother and child? Does Actinomycin I extracts into breast milk? Does Actinomycin I has any long term or short term side effects on infants? Can Actinomycin I influence milk supply or can Actinomycin I decrease milk supply in lactating mothers?
Actinomycin I lactation summary
- DrLact safety Score for Actinomycin I is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Actinomycin I may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Actinomycin I may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Actinomycin I .
- Usage of Actinomycin I is in contradiction to breastfeeding hence if it is must to use Actinomycin I and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Actinomycin I usage in lactation
Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 10 days of pumping-and-dumping.
Answer by DrLact: About Actinomycin I usage in lactation
No information is available on the use of Actinomycin I during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during Actinomycin I therapy and for 14 days after the last dose.
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