Is Dactinomycin D Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Dactinomycin D? Is Dactinomycin D safe for nursing mother and child? Does Dactinomycin D extracts into breast milk? Does Dactinomycin D has any long term or short term side effects on infants? Can Dactinomycin D influence milk supply or can Dactinomycin D decrease milk supply in lactating mothers?
Dactinomycin D lactation summary
- DrLact safety Score for Dactinomycin D is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Dactinomycin D may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Dactinomycin D may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Dactinomycin D .
- Usage of Dactinomycin D is in contradiction to breastfeeding hence if it is must to use Dactinomycin D and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Dactinomycin D usage in lactation
Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 10 days of pumping-and-dumping.
Answer by DrLact: About Dactinomycin D usage in lactation
No information is available on the use of Dactinomycin D during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during Dactinomycin D therapy and for 14 days after the last dose.
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