Is Mircera Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Mircera? Is Mircera safe for nursing mother and child? Does Mircera extracts into breast milk? Does Mircera has any long term or short term side effects on infants? Can Mircera influence milk supply or can Mircera decrease milk supply in lactating mothers?

Erythropoietin is a normal component of human milk. Methoxy polyethylene glycol-Mircera is a synthetic form of erythropoietin that slowly releases the active drug, Mircera. The excretion of exogenous methoxy polyethylene glycol-Mircera in breastmilk has not been studied; although the similar drug epoetin alfa has been studied and is considered to be acceptable during breastfeeding. If methoxy polyethylene glycol-Mircera is required by the mother, it is not a reason to discontinue breastfeeding. However, since no information is available on its use during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. A study on Holder pasteurization of breastmilk found that the erythropoietin concentration in breastmilk dropped from about 1.9 international units/L before pasteurization to about 0.5 international units/L after pasteurization.[1]

Enhancement of gastrointestinal tract maturation has been proposed as a function of erythropoietin in breastmilk.[2][3]

In small studies, epoetin alfa administration decreased serum prolactin in patients with amylotrophic lateral sclerosis,[13] but had no effect in normal subjects or in patients with renal failure undergoing chronic ambulatory peritoneal dialysis.[14][15] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.