Question

I am a breastfeeding mother and i want to know if it is safe to use Continuous erythropoietin receptor activator? Is Continuous erythropoietin receptor activator safe for nursing mother and child? Does Continuous erythropoietin receptor activator extracts into breast milk? Does Continuous erythropoietin receptor activator has any long term or short term side effects on infants? Can Continuous erythropoietin receptor activator influence milk supply or can Continuous erythropoietin receptor activator decrease milk supply in lactating mothers?

Answer by DrLact: About Continuous erythropoietin receptor activator usage in lactation

Erythropoietin is a normal component of human milk. Methoxy polyethylene glycol-Continuous erythropoietin receptor activator is a synthetic form of erythropoietin that slowly releases the active drug, Continuous erythropoietin receptor activator. The excretion of exogenous methoxy polyethylene glycol-Continuous erythropoietin receptor activator in breastmilk has not been studied; although the similar drug epoetin alfa has been studied and is considered to be acceptable during breastfeeding. If methoxy polyethylene glycol-Continuous erythropoietin receptor activator is required by the mother, it is not a reason to discontinue breastfeeding. However, since no information is available on its use during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. A study on Holder pasteurization of breastmilk found that the erythropoietin concentration in breastmilk dropped from about 1.9 international units/L before pasteurization to about 0.5 international units/L after pasteurization.[1]

Continuous erythropoietin receptor activator Side Effects in Breastfeeding

Enhancement of gastrointestinal tract maturation has been proposed as a function of erythropoietin in breastmilk.[2][3]

Continuous erythropoietin receptor activator Possible Effects in Breastfeeding

In small studies, epoetin alfa administration decreased serum prolactin in patients with amylotrophic lateral sclerosis,[13] but had no effect in normal subjects or in patients with renal failure undergoing chronic ambulatory peritoneal dialysis.[14][15] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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