Is CGP-25827A Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CGP-25827A? Is CGP-25827A safe for nursing mother and child? Does CGP-25827A extracts into breast milk? Does CGP-25827A has any long term or short term side effects on infants? Can CGP-25827A influence milk supply or can CGP-25827A decrease milk supply in lactating mothers?
CGP-25827A lactation summary
- DrLact safety Score for CGP-25827A is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of CGP-25827A is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that CGP-25827A does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of CGP-25827A safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CGP-25827A usage in lactation
Bronchodilator of long-lasting action. At latest update no published data on excretion into breast milk were found. Terbutaline which is a compound closely related to Formoterol is excreted into breast milk in non-significant amount.Salmeterol, another compound with similar characteristics, is also non-significantly excreted. With a relatively high molecular weight, excretion into breast milk seems unlikely. Expert consensus states that the use of inhaled bronchodilators is compatible with breastfeeding due to a minimal absorption and low levels achieved in the mother's plasma. Inhaled therapy with bronchodilators is preferred since they use a lower dose (less likelihood of excretion into milk)