Is ASP 2215 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use ASP 2215? Is ASP 2215 safe for nursing mother and child? Does ASP 2215 extracts into breast milk? Does ASP 2215 has any long term or short term side effects on infants? Can ASP 2215 influence milk supply or can ASP 2215 decrease milk supply in lactating mothers?

Answer by DrLact: About ASP 2215 usage in lactation

No information is available on ASP 2215 during breastfeeding. It is 94% bound to plasma proteins, so amounts in milk are likely to be low; however, it has a long half-life of about 113 hours. The manufacturer recommends that breastfeeding be discontinued during ASP 2215 therapy and for 2 months after the last dose.

Alternate Drugs

Niraparib

Azelaic Acid(Safe)

Binimetinib

Dasatinib(Unsafe)

Neratanib

Fluorouracil(Dangerous)

Cisplatin(Unsafe)

Docetaxel(Dangerous)

Alemtuzumab(Low Risk)

Dactinomycin(Dangerous)

Busulfan(Dangerous)

Rituximab(Low Risk)

Gemcitabine(Dangerous)

Bevacizumab(Low Risk)

Copanlisib

Thioguanine(Dangerous)

Nilotinib(Unsafe)

Pazopanib(Unsafe)

Vincristine(Dangerous)

Letrozole(Dangerous)

Tamoxifen(Dangerous)

Erlotinib(Unsafe)

Emicizumab

Dinutuximab

Midostaurin

Trastuzumab(Unsafe)

Ado-Trastuzumab Emtansine

Exemestane(Dangerous)

Idelalisib

Obinutuzumab

Mitoxantrone(Dangerous)

Pembrolizumab

Ruxolitinib

Regorafenib

Cladribine(Dangerous)

Inotuzumab Ozogamicin

Mercaptopurine(Safe)

Nivolumab(Unsafe)

Ipilimumab(Unsafe)

Hydroxyurea(Low Risk)

Vinblastine(Dangerous)

Avelumab

Cobimetinib

Cetuximab(Unsafe)

Etoposide(Dangerous)

Gefitinib

Acalabrutinib

Bleomycin(Dangerous)

Imatinib(Unsafe)

Carboplatin(Dangerous)

Moxetumomab Pasudotox

Doxorubicin(Dangerous)

Vinorelbine(Dangerous)

Tretinoin

Lapatinib

Paclitaxel(Dangerous)

Topotecan

Crizotinib

Cyclophosphamide(Dangerous)

Dacarbazine(Dangerous)

Gemcitabine(Dangerous)

Orlistat(Low Risk)

Nilotinib(Unsafe)

Pazopanib(Unsafe)

Allopurinol(Safe)

Erlotinib(Unsafe)

Imatinib(Unsafe)

Dasatinib(Unsafe)

Nilotinib(Unsafe)

Pazopanib(Unsafe)

Erlotinib(Unsafe)

Imatinib(Unsafe)

Dasatinib(Unsafe)

Nilotinib(Unsafe)

Pazopanib(Unsafe)

Erlotinib(Unsafe)

Imatinib(Unsafe)

Dasatinib(Unsafe)

Nilotinib(Unsafe)

Pazopanib(Unsafe)

Erlotinib(Unsafe)

Imatinib(Unsafe)

Dasatinib(Unsafe)

Synonyms of ASP 2215

UNII-66D92MGC8M

2-Pyrazinecarboxamide, 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)-

ASP2215

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.