Is PF-04449913 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use PF-04449913? Is PF-04449913 safe for nursing mother and child? Does PF-04449913 extracts into breast milk? Does PF-04449913 has any long term or short term side effects on infants? Can PF-04449913 influence milk supply or can PF-04449913 decrease milk supply in lactating mothers?
Answer by DrLact: About PF-04449913 usage in lactation
No information is available on PF-04449913 during breastfeeding. It is 91% bound to plasma proteins, so amounts in milk are likely to be low. With a half-life of 17.4 hours, it is likely to be eliminated from milk by 4 to 7 days after the last dose. However, the manufacturer recommends that breastfeeding be discontinued during PF-04449913 therapy and for at least 30 days after the last dose.
Alternate Drugs
Fluorouracil(Dangerous)
Dacarbazine(Dangerous)
Alemtuzumab(Low Risk)
Letrozole(Dangerous)
Dasatinib(Unsafe)
Rituximab(Low Risk)
Exemestane(Dangerous)
Bevacizumab(Low Risk)
Erlotinib(Unsafe)
Thioguanine(Dangerous)
Vincristine(Dangerous)
Pazopanib(Unsafe)
Tamoxifen(Dangerous)
Nilotinib(Unsafe)
Mitoxantrone(Dangerous)
Mercaptopurine(Safe)
Trastuzumab(Unsafe)
Docetaxel(Dangerous)
Hydroxyurea(Low Risk)
Etoposide(Dangerous)
Dactinomycin(Dangerous)
Ipilimumab(Unsafe)
Doxorubicin(Dangerous)
Nivolumab(Unsafe)
Imatinib(Unsafe)
Cladribine(Dangerous)
Gemcitabine(Dangerous)
Cetuximab(Unsafe)
Cyclophosphamide(Dangerous)
Vinblastine(Dangerous)
Carboplatin(Dangerous)
Cisplatin(Unsafe)
Bleomycin(Dangerous)
Azelaic Acid(Safe)
Paclitaxel(Dangerous)
Busulfan(Dangerous)
Vinorelbine(Dangerous)
Dasatinib(Unsafe)
Orlistat(Low Risk)
Erlotinib(Unsafe)
Allopurinol(Safe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Gemcitabine(Dangerous)
Dasatinib(Unsafe)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Nilotinib(Unsafe)
Imatinib(Unsafe)
Dasatinib(Unsafe)