Is Brivudina [INN-Spanish] Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Brivudina [INN-Spanish]? Is Brivudina [INN-Spanish] safe for nursing mother and child? Does Brivudina [INN-Spanish] extracts into breast milk? Does Brivudina [INN-Spanish] has any long term or short term side effects on infants? Can Brivudina [INN-Spanish] influence milk supply or can Brivudina [INN-Spanish] decrease milk supply in lactating mothers?

Brivudina [INN-Spanish] lactation summary

Brivudina [INN-Spanish] usage has low risk in breastfeeding

DrLact safety Score for Brivudina [INN-Spanish] is 3 out of 8 which is considered Low Risk as per our analyses.
A safety Score of 3 indicates that usage of Brivudina [INN-Spanish] may cause some minor side effects in breastfed baby.
Our study of different scientific research indicates that Brivudina [INN-Spanish] may cause moderate to no side effects in lactating mother.
Most of scientific studies and research papers declaring usage of Brivudina [INN-Spanish] low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
While using Brivudina [INN-Spanish] We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Brivudina [INN-Spanish] usage in lactation

Medication used for treatment of Herpes zoster infection. At latest update, relevant published data on excretion into breast milk were not found. Because a high distribution volume (DV) and high protein-binding capacity, excretion into breast milk in significant amount is very unlikely. A low oral bioavailability impairs the pass of it from the mother's milk to the infant's plasma, except in prematures or in the early neonatal period, when a higher intestinal absorption may occur. Until more data on this medication is available, safer alternative drugs are preferred, especially in such critical age periods.

Alternate Drugs for Antivirals for systemic use. ATC J05

Acyclovir(Safe)

Famciclovir(Low Risk)

Oseltamivir(Safe)

Abacavir(Safe)

Didanosine(Unsafe)

Efavirenz(Unsafe)

Emtricitabine(Safe)

Indinavir(Unsafe)

Lamivudine(Safe)

Nelfinavir(Unsafe)

Nevirapine(Low Risk)

Ritonavir(Unsafe)

Saquinavir(Unsafe)

Tenofovir(Safe)

Zidovudine(Low Risk)

Zanamivir(Safe)

Ribavirin(Low Risk)

Dasabuvir(Low Risk)

Daclatasvir(Low Risk)

Ombitasvir(Low Risk)

Ledipasvir(Low Risk)

Sofosbuvir(Low Risk)

Simeprevir(Low Risk)

Velpatasvir(Low Risk)

Ganciclovir(Low Risk)

Valganciclovir(Low Risk)

Adefovir Dipivoxil(Unsafe)

Oseltamivir Phosphate(Safe)

Amprenavir(Unsafe)

Brivudine(Low Risk)

Valaciclovir(Safe)

Cidofovir(Unsafe)

Foscarnet(Unsafe)

Lysozyme(Safe)

Rimantadine Hydrochloride(Low Risk)

Zalcitabine(Unsafe)

Tribavirin(Low Risk)

Globulin G1(Safe)

Azidothymidine(Low Risk)

Azt(Low Risk)

Muramidase(Safe)

Aciclovir(Safe)

BW-248U(Safe)

Ddi(Unsafe)

Acycloguanosine(Safe)

Synonyms of Brivudina [INN-Spanish]

Brivudinum [INN-Latin]

(E)-5-(2-Bromovinyl)-deoxyuridine

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.