Is L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine? Is L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine safe for nursing mother and child? Does L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine extracts into breast milk? Does L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine has any long term or short term side effects on infants? Can L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine influence milk supply or can L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine decrease milk supply in lactating mothers?
L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine lactation summary
- DrLact safety Score for L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine usage in lactation
Precursor of Aciclovir which is used for treatment of infections due to Herpes zoster and Herpes simplex viruses and the prevention of Cytomegalovirus infection in immunocompromised patients. It is excreted into breast milk as Aciclovir in non-significant clinical amount, with no side-effects observed among breastfed infants from treated mothers. Urine levels of Aciclovir in those infants were shown to be very low.
Alternate Drugs for Antivirals for systemic use. ATC J05
Acyclovir(Safe)
Famciclovir(Low Risk)
Oseltamivir(Safe)
Abacavir(Safe)
Didanosine(Unsafe)
Efavirenz(Unsafe)
Emtricitabine(Safe)
Indinavir(Unsafe)
Lamivudine(Safe)
Nelfinavir(Unsafe)
Nevirapine(Low Risk)
Ritonavir(Unsafe)
Saquinavir(Unsafe)
Tenofovir(Safe)
Zidovudine(Low Risk)
Zanamivir(Safe)
Ribavirin(Low Risk)
Dasabuvir(Low Risk)
Daclatasvir(Low Risk)
Ombitasvir(Low Risk)
Ledipasvir(Low Risk)
Sofosbuvir(Low Risk)
Simeprevir(Low Risk)
Velpatasvir(Low Risk)
Ganciclovir(Low Risk)
Valganciclovir(Low Risk)
Adefovir Dipivoxil(Unsafe)
Oseltamivir Phosphate(Safe)
Amprenavir(Unsafe)
Brivudine(Low Risk)
Valaciclovir(Safe)
Cidofovir(Unsafe)
Foscarnet(Unsafe)
Lysozyme(Safe)
Rimantadine Hydrochloride(Low Risk)
Zalcitabine(Unsafe)
Tribavirin(Low Risk)
Globulin G1(Safe)
Azidothymidine(Low Risk)
Azt(Low Risk)
Muramidase(Safe)
Aciclovir(Safe)
BW-248U(Safe)
Ddi(Unsafe)
Acycloguanosine(Safe)