Question

I am a breastfeeding mother and i want to know if it is safe to use (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine? Is (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine safe for nursing mother and child? Does (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine extracts into breast milk? Does (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine has any long term or short term side effects on infants? Can (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine influence milk supply or can (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine decrease milk supply in lactating mothers?

(S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine lactation summary

(S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine is unsafe in breastfeeding
  • DrLact safety Score for (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine .
  • It is recommended to evaluate the advantage of not breastfeeding while using (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine Vs not using (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine And continue breastfeeding.
  • While using (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine usage in lactation

Toxic for the kidney. When IV administered it can reach a serum level of 20 mg/L Excretion into breast milk is unknown but intestinal absoption should be very poor.

Alternate Drugs for Antivirals for systemic use. ATC J05

Acyclovir(Safe)
Famciclovir(Low Risk)
Abacavir(Safe)
Didanosine(Unsafe)
Efavirenz(Unsafe)
Indinavir(Unsafe)
Nelfinavir(Unsafe)
Nevirapine(Low Risk)
Ritonavir(Unsafe)
Saquinavir(Unsafe)
Tenofovir(Safe)
Zidovudine(Low Risk)
Zanamivir(Safe)
Ribavirin(Low Risk)
Dasabuvir(Low Risk)
Daclatasvir(Low Risk)
Ombitasvir(Low Risk)
Ledipasvir(Low Risk)
Sofosbuvir(Low Risk)
Simeprevir(Low Risk)
Velpatasvir(Low Risk)
Ganciclovir(Low Risk)
Valganciclovir(Low Risk)
Amprenavir(Unsafe)
Brivudine(Low Risk)
Cidofovir(Unsafe)
Foscarnet(Unsafe)
Lysozyme(Safe)
Zalcitabine(Unsafe)
Tribavirin(Low Risk)
Azidothymidine(Low Risk)
Azt(Low Risk)
Aciclovir(Safe)
BW-248U(Safe)
Ddi(Unsafe)

Synonyms of (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.