Is 1,8-Diacetoxyanthraquinone-3-carboxylic acid Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1,8-Diacetoxyanthraquinone-3-carboxylic acid? Is 1,8-Diacetoxyanthraquinone-3-carboxylic acid safe for nursing mother and child? Does 1,8-Diacetoxyanthraquinone-3-carboxylic acid extracts into breast milk? Does 1,8-Diacetoxyanthraquinone-3-carboxylic acid has any long term or short term side effects on infants? Can 1,8-Diacetoxyanthraquinone-3-carboxylic acid influence milk supply or can 1,8-Diacetoxyanthraquinone-3-carboxylic acid decrease milk supply in lactating mothers?
1,8-Diacetoxyanthraquinone-3-carboxylic acid lactation summary
- DrLact safety Score for 1,8-Diacetoxyanthraquinone-3-carboxylic acid is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1,8-Diacetoxyanthraquinone-3-carboxylic acid may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1,8-Diacetoxyanthraquinone-3-carboxylic acid may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1,8-Diacetoxyanthraquinone-3-carboxylic acid low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1,8-Diacetoxyanthraquinone-3-carboxylic acid We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1,8-Diacetoxyanthraquinone-3-carboxylic acid usage in lactation
It metabolizes to rein (rhubarb anthraquinone glycoside). Most possible serious effect is diarrhea. Due to higher %protein binding, excretion to breast milk are unlikely. Absorption through the child’s gut is interfered by the calcium contained in the milk.
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Indomethacin(Safe)
Ketorolac(Safe)
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Rofecoxib(Unsafe)
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