Is Diacetylrhein Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Diacetylrhein? Is Diacetylrhein safe for nursing mother and child? Does Diacetylrhein extracts into breast milk? Does Diacetylrhein has any long term or short term side effects on infants? Can Diacetylrhein influence milk supply or can Diacetylrhein decrease milk supply in lactating mothers?
Diacetylrhein lactation summary
- DrLact safety Score for Diacetylrhein is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Diacetylrhein may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Diacetylrhein may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Diacetylrhein low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Diacetylrhein We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Diacetylrhein usage in lactation
It metabolizes to rein (rhubarb anthraquinone glycoside). Most possible serious effect is diarrhea. Due to higher %protein binding, excretion to breast milk are unlikely. Absorption through the child’s gut is interfered by the calcium contained in the milk.
Alternate Drugs for Antiinflammatory and antirheumatic products, non-steroids and others specific. ATC M01A-C
Auranofin(Low Risk)
Celecoxib(Safe)
Diclofenac(Safe)
Etodolac(Low Risk)
Fenoprofen(Safe)
Flurbiprofen(Safe)
Ibuprofen(Safe)
Indomethacin(Safe)
Ketorolac(Safe)
Meclofenamate(Low Risk)
Mefenamic Acid(Safe)
Meloxicam(Low Risk)
Nabumetone(Low Risk)
Naproxen(Low Risk)
Penicillamine(Low Risk)
Piroxicam(Safe)
Sulindac(Low Risk)
Tolmetin(Safe)
Oxaprozin(Low Risk)
Ketoprofen(Safe)
Glucosamine(Safe)
Apazone(Safe)
Niflumic Acid(Low Risk)
Nimesulide(Unsafe)
Parecoxib(Low Risk)
Proglumetacin(Unsafe)
Rofecoxib(Unsafe)
Azapropazone(Safe)
Aceclofenac(Safe)
Aurothiomalate Sodium(Low Risk)
Clonixin(Low Risk)
Dexibuprofen(Safe)
Dexketoprofen(Safe)
Diacerein(Low Risk)
Etoricoxib(Low Risk)
Phenylbutazone(Safe)
Lornoxicam(Low Risk)
Loxoprofen(Low Risk)
Meclofenamic Acid(Low Risk)
Diclofenac Potassium(Safe)
Diclofenac Sodium(Safe)
Chitosamine(Safe)
Azapropazon(Safe)
Ibuprofen Lysine(Safe)
Etodolic Acid(Low Risk)
Indometacin(Safe)
Indomethacin Sodium(Safe)
Butadione(Safe)