Is UNII-75HGV0062C Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-75HGV0062C? Is UNII-75HGV0062C safe for nursing mother and child? Does UNII-75HGV0062C extracts into breast milk? Does UNII-75HGV0062C has any long term or short term side effects on infants? Can UNII-75HGV0062C influence milk supply or can UNII-75HGV0062C decrease milk supply in lactating mothers?
UNII-75HGV0062C lactation summary
- DrLact safety Score for UNII-75HGV0062C is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-75HGV0062C may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-75HGV0062C may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-75HGV0062C low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-75HGV0062C We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-75HGV0062C usage in lactation
Heparin-like glycosaminoglycan which is a mixture of low molecular weight heparin (80%) and dermatan sulfate (20%) that has hypolipaemic and antithrombotic properties and used for treatment of venous insufficiency.It does not have significant effects on coagulation but some protective properties on vascular endothelium is attributed. At latest update on excretion into breast milk no published data were found. Pharmacokinetic data (large volume of distribution and high molecular weight) make it unlikely the passage into milk in significant amounts. Until more published data about this drug regarding breastfeeding is available, a safer alternative should be used, especially during the neonatal period and in case of prematurity.
Alternate Drugs for Antithrombotic agents: Heparin group. ATC B01AB
Dalteparin(Safe)
Enoxaparin(Safe)
Heparin(Safe)
Bemiparin Sodium(Safe)
Dalteparin Sodium(Safe)
Enoxaparin Sodium(Safe)
Nadroparin Calcium(Safe)
Reviparin Sodium(Safe)
Tinzaparin-Sodium(Safe)
Parnaparin Sodium(Safe)
Ardeparin Sodium(Safe)
Certoparin Sodium(Safe)
Sulodexide(Low Risk)
Heparin Calcium(Safe)
Heparin Sodium(Safe)
Nadroparine(Safe)