Is Simeprevir Sodium Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Simeprevir Sodium? Is Simeprevir Sodium safe for nursing mother and child? Does Simeprevir Sodium extracts into breast milk? Does Simeprevir Sodium has any long term or short term side effects on infants? Can Simeprevir Sodium influence milk supply or can Simeprevir Sodium decrease milk supply in lactating mothers?
Simeprevir Sodium lactation summary
- DrLact safety Score for Simeprevir Sodium is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Simeprevir Sodium may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Simeprevir Sodium may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Simeprevir Sodium low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Simeprevir Sodium We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Simeprevir Sodium usage in lactation
Used alone or in combination with sofosbuvir in the treatment of hepatitis C. Since the last update we have not found published data on its excretion in breast milk. Its pharmacokinetic data (slightly elevated molecular weight and very high percentage of plasma protein binding) make it very unlikely that significant amounts will pass into milk, so that although there is disagreement (Thompson 2016), other experts believe that treatment with Simeprevir, on its own or in combination with Sofosbuvir is not contraindicated during breastfeeding (LactMed 2016, See below the information of these related products: