Question

I am a breastfeeding mother and i want to know if it is safe to use Acyclovir? Is Acyclovir safe for nursing mother and child? Does Acyclovir extracts into breast milk? Does Acyclovir has any long term or short term side effects on infants? Can Acyclovir influence milk supply or can Acyclovir decrease milk supply in lactating mothers?

Acyclovir lactation summary

Acyclovir is safe in breastfeeding
  • DrLact safety Score for Acyclovir is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Acyclovir is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Acyclovir does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Acyclovir safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Acyclovir usage in lactation

Antiviral very active against herpes simplex and zoster-varicella.Intravenous, oral and topical (dermatological and ophthalmological) administration.Authorized use in newborns and infants. It is excreted in breast milk in clinically insignificant amounts, much lower than the dose used in newborns and infants (Drake 2012, Bork 1995, Taddio 1994, Don 1991, Meyer 1988, Lau 1987), and no problems have been observed in infants whose mothers were taking acyclovir (Taddio 1994). There is not systemic absorption of topical Acyclovir. List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002).American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).

Answer by DrLact: About Acyclovir usage in lactation

Even with the highest maternal dosages, the dosage of acyclovir in milk is only about 1% of a typical infant dosage and would not be expected to cause any adverse effects in breastfed infants. Topical acyclovir applied to small areas of the mother's body away from the breast should pose no risk to the infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

Acyclovir Side Effects in Breastfeeding

The mother of a 4-month-old infant noticed no adverse effects in her breastfed infant while she was taking an acyclovir dosage of 800 mg orally 5 times daily.[5]

Alternate Drugs

Naftifine(Safe)
Cefoxitin(Safe)
Ritonavir(Unsafe)
Gatifloxacin(Low Risk)
Dapsone(Low Risk)
Ofloxacin(Safe)
Cefotetan(Safe)
Abacavir(Safe)
Enoxacin(Low Risk)
Capreomycin(Low Risk)
Malathion(Low Risk)
Doxycycline(Low Risk)
Ertapenem(Safe)
Neomycin(Safe)
Amikacin(Safe)
Nafcillin(Safe)
Nevirapine(Low Risk)
Demeclocycline(Low Risk)
Zidovudine(Low Risk)
Moxifloxacin(Low Risk)
Lindane(Unsafe)
Cefixime(Safe)
Valganciclovir(Low Risk)
Cefepime(Safe)
Famciclovir(Low Risk)
Methicillin(Low Risk)
Nelfinavir(Unsafe)
Econazole(Safe)
Erythromycin(Low Risk)
Efavirenz(Unsafe)
Meropenem(Safe)
Ganciclovir(Low Risk)
Cefdinir(Safe)
Tenofovir(Safe)
Clindamycin(Low Risk)
Cefazolin(Safe)
Didanosine(Unsafe)
Lomefloxacin(Low Risk)
Levofloxacin(Low Risk)
Cefaclor(Safe)
Kanamycin(Safe)
Primaquine(Low Risk)
Acyclovir(Safe)
Atovaquone(Low Risk)
Saquinavir(Unsafe)
Quinine(Safe)
Linezolid(Low Risk)
Amantadine(Low Risk)
Cefprozil(Safe)
Aztreonam(Safe)
Indinavir(Unsafe)
Rifaximin(Safe)
Ritonavir(Unsafe)
Sofosbuvir(Low Risk)
Abacavir(Safe)
Ledipasvir(Low Risk)
Ombitasvir(Low Risk)
Nevirapine(Low Risk)
Zidovudine(Low Risk)
Daclatasvir(Low Risk)
Valganciclovir(Low Risk)
Famciclovir(Low Risk)
Dasabuvir(Low Risk)
Nelfinavir(Unsafe)
Ribavirin(Low Risk)
Efavirenz(Unsafe)
Ganciclovir(Low Risk)
Tenofovir(Safe)
Didanosine(Unsafe)
Acyclovir(Safe)
Saquinavir(Unsafe)
Amantadine(Low Risk)
Velpatasvir(Low Risk)
Indinavir(Unsafe)
Zanamivir(Safe)
Simeprevir(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.